Trace mineral changes in response to organic and inorganic selenium supplementation

Twenty-one Lori–Bakhtiary sheep were randomly allocated into 3 groups to compare the effects of oral selenium nano particles (Se NPs) and sodium selenite (Na-Se) supplementation on serum selenium, copper, zinc, molybdenum, manganese and cobalt concentration. Groups 1 and 2 orally received Se NPs and Na-Se (1 mg/kg) for 10 consecutive days, respectively and group 3 were considered as control group. Blood samples were taken on the days 0, 10, 20 and 30, and minerals were measured using atomic absorption spectrophotometery. The obtained results showed that selenium, copper and manganese concentration increased and zinc level decreased significantly in both treated groups (P<0.05). In addition, serum molybdenum concentration increased in response to oral Na-Se supplementation on the days 10 and 20 compared to the basal level and also the control group (P<0.05). Findings explain the interaction between selenium derivates and other elements in which the role of Se NPs was considerable in increasing Cu and Mn level and the role of Na-Se noticeable increasing serum molybdenum concentration.